Association Z-scores for 721 variants in a 2.99 Mb window on chromosome 10 (103,008,802-105,997,104), from the Psychiatric Genomics Consortium's second schizophrenia GWAS wave (PGC SCZ2).
Usage
data(PGC2_3Mb)Format
A data.frame with 721 rows and 6 columns:
- rsid
dbSNP rs identifier.
- chr
Chromosome;
10throughout.- bp
Base pair position.
- a1
Reference allele.
- a2
Alternative allele.
- z
Association Z-score.
Details
The small window makes this the example input for the functions whose cost
grows with the square of the number of variants in the region:
computeLD and dist.
References
Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature 511(7510):421-427. doi:10.1038/nature13595