Study reference-allele frequencies for the 13,362 chromosome 22 variants of the Psychiatric Genomics Consortium's second schizophrenia GWAS wave (PGC SCZ2) that were measured on the Illumina 1M array.
Usage
data(PGC2_Chr22_ilmn1M_AF1)Format
A data.frame with 13,362 rows and 6 columns:
- rsid
dbSNP rs identifier.
- chr
Chromosome;
22throughout.- bp
Base pair position.
- a1
Reference allele.
- a2
Alternative allele.
- af1
Frequency of
a1in the study cohort.
Details
This is the example input for afmix, which estimates a
cohort's ancestry proportions by matching its allele frequencies against the
reference panel. It covers the same variants, in the same order, as
PGC2_Chr22_ilmn1M_Z, and the proportions estimated from it are
shipped as PGC2_SCZ_ANC_Prop.
References
Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature 511(7510):421-427. doi:10.1038/nature13595